Search Studies
Research studies are looking for volunteers just like you. Both healthy volunteers and participants with specific health conditions are needed to help answer important questions impacting the health of our friends and family. Join us to improve the health of others.
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Study for Rural Well-Being and Social Connection
Official Title Fostering Agricultural Relationships and Meaning - Thriving on Kinship (FARM-TOK)Purpose
The purpose of this study is to understand how well and how accepted a phone-based intervention for loneliness works for people in rural or farming/agricultural areas. The goal of this intervention is to reduce loneliness and improve mental well-being.
Could this study be right for you?
Inclusion criteria
- Understand English
- Reside in an agricultural area in Ohio
- Experiencing loneliness or social isolation
Exclusion Criteria
- Limited mental competency/not able to give informed consent
- Non-English Speaking
- Diagnosis of neurological disorder or Bipolar I
- Current psychotic diagnosis
- Suicidal or homicidal intent indicating need for hospitalization or treatment (as determined by clinical interviewer)
Age Range
18 years and up -
A Study Evaluating How Dietary Oils Effect Muscle Function and Strength
Official Title The Foods and Oils to Repair Correct and Enhance Strength (FORCES) Study: Determining the effect of dietary oils on muscle function, strength and massPurpose
The purpose of the FORCES Study is to determine how dietary oils effect muscle function, strength and mass in older adults who feel their muscle function and strength has declined with age.
During this 27-week study participants will
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Consume ~2.5 tsp of oil each day through foods
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Complete muscle function and strength testing
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Have their blood drawn
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Have their body weight and composition measured
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Have an MRI scan of your legs, if able
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Fill out questionnaires
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Collect a small amount of muscle tissue from the leg (muscle biopsy
Could this study be right for you?
Feel your muscle function, strength or mass as decreased with age
Do NOT have food allergies
Are not taking any weight loss medications or following a weight loss program
Age Range
65 - 80 years -
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At home activity study examining children's early learning and development.
Official Title Learning Interactions Made for Everyone (LIME)Purpose
This study will examine activities of caregivers and their preschool aged child over a 12-week period. Caregivers will track learning activities with their child over the 12-weeks. Some participants will be asked to engage in additional learning activities with their child. Researchers will conduct assessments with the child before and after the 12-week program, as well as brief follow-ups 3-, 6-, and 12- months after completion. The total duration of participation in this study is up to 24 hours. The study will identify strategies in home-based learning activities and inform development of interventions to improve school readiness among children.
Could this study be right for you?
Child is minimally verbal in English.
Caregiver understands enough English to understand intervention materials.
Child does not have a severe intellectual disability.
Caregiver and child reside in the greater Columbus area.
Age Range
42 - 57 months -
Ketogenic Diet Intervention to Improve Response to Immunotherapy: KetoIO
Official Title Phase I Study of the Safety and Feasibility of a Ketogenic Dietary Intervention to Improve Response to ImmunotherapyPurpose
This study will look at if a ketogenic diet (KD) can help treatment work better in patients with metastatic melanoma or metastatic kidney cancer. People who take part in the study will be randomly assigned to either continue eating their usual diet or trying the KD diet for 24 weeks. Participants will have blood and stool samples collected during the study. They will also test their sugar by doing daily glucose fingers sticks. Participants may be paid up to $200 for taking part in the study.
Could this study be right for you?
- Patients with metastatic melanoma receiving first-line treatment with immunotherapy or Patients with metastatic renal cell cancer receiving first line treatment with immunotherapy.
- Willing to give three stool samples
- Willing to participate in a ketogenic diet (KD)
Age Range
18 years and up -
The Perceptions of Gen Zs Regarding the Dietary Guidelines for Americans (DGA)
Official Title The Knowledge and Perceptions of Gen Zs Regarding the Dietary Guidelines for AmericansPurpose
- Use ideas from Social Cognitive Theory to describe Gen Zs regarding the Dietary Guidelines for Americans (DGA) 2020 to 2025
- Explain what Gen Z knows and believes regarding the MyPlate recommendations for healthy eating related to:
- Filling half their plate with fruit and vegetables
- Filling one-quarter of their plate with lean protein, and varying the sources of protein
- Filling one-quarter of their plate with grains, making half of the grains whole grains
- To describe the associations between demographic variables (ethnicity, education, household income, and home environment) and Gen Zs perceptions and knowledge of the DGA
Could this study be right for you?
18 to 28 years old
Live in the US
English speaker
Have access to a device that supports Zoom
Age Range
18 - 28 years -
Smartphone-based HIV-specific Smoking Cessation Study
Official Title AMC-111 Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living With HIV: A Feasibility StudyPurpose
This clinical trial evaluates the usefulness of using a smartphone-based HIV-specific smoking cessation intervention at the time of lung cancer screening in helping people living with HIV quit smoking. Positively Smoke Free - Mobile may help patients with HIV quit smoking.
In this study, you will have lung cancer screening performed via a CT scan. You will also be enrolled into a self-guided smartphone-based HIV-specific smoking cessation intervention called “Positively Smoke Free - Mobile” lasting 42 days. After starting the intervention, you will be evaluated at 3, 6, and 12 months.
Could this study be right for you?
Must have at least a 20 pack-year history of smoking (a way to measure how much a person has smoked over time, 1 pack-year is a pack per day for a year or 2 packs of cigarettes for half a year, etc.)
Must have not had a CT scan in the past 12 months
HIV positive, and must be receiving antiretroviral therapy and have a CD4 count of at least 200cells/uL within 6 months of enrolling in the study
Able to understand and provide informed consent
Possess a smart phone that can browse the web
Not receiving any other smoking cessation interventions currently or within the prior 30 days
Female volunteers cannot be pregnant, lactating, or breast-feeding
Age Range
45 - 80 years -
DAANCE FOR CHEMOTHERAPY-INDUCED NEUROPATHY (DAANCE)
Official Title Dance-Based Avenues to Advance Nonpharmacologic Treatment of Chemotherapy Effects (DAANCE): A Multi-Center TrialPurpose
This study will teach tango dance to try to help with neuropathy symptoms. Tango dancing classes will take place for 2 times a week for 8 weeks. You will be asked about symptoms such as numbness, tingling, fatigue, pain, and balance. There is a 6 month follow up period where we will ask you to tell us about your symptoms via an app.
Could this study be right for you?
- Breast cancer survivors stage I-IV
- Exposure to chemotherapy with the last exposure being at least 3 months prior to study participation
- Must be ambulatory
Age Range
40 years and up -
A Study to Evaluate Remibrutinib in Adults with Moderate to Severe Hidradenitis Suppurativa
Official Title A randomized, double-blind, double-dummy, placebo-controlled, multicenter, Phase 3 study assessing the efficacy, safety, and tolerability of 2 doses of remibrutinib over a 68-week treatment period in adult patients with moderate to severe hidradenitis suppurativaPurpose
This study is being done to see how well remibrutinib works for people who have hidradenitis suppurativa
Could this study be right for you?
- Subject must have a diagnosis of moderate to severe hidradenitis suppurativa (HS) for at least 6 months with lesions in 2 distinct areas
- Subject must be in good general health with no history of tuberculosis, HIV, or hepatitis B or C
- Subject must have no recent history (within 6 months) of significant medical conditions such as a heart attack or stroke
- Subject must not be taking anticoagulant medication (ex. warfarin) or dual anti-platelet therapy (ex. acetylsalicylic acid + clopidogrel)
Age Range
18 years and up -
A Long-term, observational study on the safety of TZIELD for patients with Stage 2, Type 1 Diabetes
Official Title AN OBSERVATIONAL, LONG-TERM SAFETY STUDY OF TZIELD® (TEPLIZUMAB-MZWV) IN PATIENTS WITH STAGE 2 TYPE 1 DIABETESPurpose
The objective of the study is to test the safety and efficacy of TZIELD over the course of 10 years in patients with Stage 2, Type 1 Diabetes, as well as the prevention of Stage 3, Type 1 Diabetes.
Could this study be right for you?
Inclusion Criteria:
TZIELD-Exposed Cohort
1. Patients in the US diagnosed with Stage 2 T1D who are planned to initiate TZIELD treatment according to the currently approved label or who have initiated TZIELD treatment within 6 months prior to enrollment:
− Day 1: 65 μg/m²
− Day 2: 125 μg/m²
− Day 3: 250 μg/m²
− Day 4: 500 μg/m²
− Days 5 through 14: 1,030 μg/m² per day
− Cumulative dose is approximately 11,240 μg/m²2. Appropriate written informed consent/assent as applicable for the age of the patient
TZIELD-Unexposed Cohort
1. Patients in the US diagnosed with Stage 2 T1D but who are not treated with TZIELD
2. Appropriate written informed consent/assent as applicable for the age of the patient
Exclusion Criteria:
1. Patients who initiated TZIELD treatment more than 6 months prior to enrollment
2. Patients who had participated in a previous clinical trial for TZIELD
3. Patients in an ongoing clinical trial of an investigational product or who had ended participation within 6 months prior to study enrollment; patients participating in other observational studies may be enrolled.Age Range
18 - 70 years -
Research Study on the Biomechanics of Total Knee Replacements
Official Title Biomechanical Metrics of Movement Relative to Total Knee ArthroplastyPurpose
This study aims to understand how a total knee replacement surgery (TKR) affects muscle function and movement in the lower body. It focuses on four key areas:
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Examining how TKR changes the way muscles work in the lower body.
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Exploring how these muscle changes relate to the forces people experience when walking and doing daily activities after surgery.
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Connecting muscle function to how well patients feel and move after TKR.
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Identifying different types of TKR patients based on their physical traits, movement patterns, and medical history to see how they compare.
Could this study be right for you?
- Must be scheduled to receive a total knee replacement within the next 2 months
- Have a body mass index (BMI) < 40
- Do not require the use of a cane or other assistive device when walking, climbing stairs, and getting up from a chair
Exclusion criteria varies; please contact Study Coordinator for more information
Age Range
18 years and up -
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Impacts of Ketone Esters on Exercise and Heart Health in Type 2 Diabetics
Official Title Effects of Acute and Chronic Ketone Ester Consumption on Exercise Tolerance and Cardiac Function in Subjects with DiabetesPurpose
This placebo-controlled study is being done to evaluate the effects of a ketone ester drink on exercise performance and heart health in a group of subjects diagnosed with type 2 diabetes.
Could this study be right for you?
There are additional exclusion criteria, study staff will screen fully before enrollment.
Age Range
18 - 80 years -
Radiotracer Imaging of Lower Extremity Skeletal Muscle Perfusion in Patients with Peripheral Arterial Disease (PAD)
Official Title Radiotracer Imaging of Lower Extremity Skeletal Muscle Perfusion in Patients with Peripheral Arterial DiseasePurpose
The purpose of the study is to evaluate the usefulness of a new imaging method that measures blood flow to the calves and feet.
A group of patients with a history of peripheral artery disease (PAD) will have blood flow to their legs and/or feet evaluated using a nuclear imaging technique called positron emission tomography (PET). A separate group of patients with PAD who are scheduled to undergo a revascularization procedure on their leg (such as balloon angioplasty, stent placement, or bypass surgery) will undergo PET imaging before and after their surgical intervention to evaluate how the intervention improved blood flow to their leg.
In addition to patients with PAD undergoing imaging studies, we will also recruit and image healthy volunteers to establish a normal healthy database of blood flow values for our new imaging method.
Patients with PAD will be evaluated for up to 18 months after their imaging study visit to evaluate how their blood flow values are related to their clinical outcomes, such as rates of diabetic wound healing and amputation. Outcomes will be monitored through medical chart review and through follow-up visits at OSU-affiliated clinics.
Could this study be right for you?
We are interested in recruiting healthy volunteers with no known history of cardiovascular disease or diabetes mellitus.
OR
Patients with previously diagnosed peripheral artery disease.
Age Range
18 years and up