Search Studies

Official Title Evaluation of Wear Experience with PRECISION7® Contact lenses in habitual Acuvue® Oasys® lens wearers

Purpose

The purpose of this study is explorative, evaluating the overall wear experience of individuals who normally wear contact lenses after being refit into each of the two study lenses and wearing them each over 2 weeks.

Could this study be right for you?

• Adults who wear Acuvue® Oasys® contact lenses.
• Ability to attend 3 visits over the course of 4 weeks.
• Satisfy all other study eligibility and exclusion criteria.

Age Range

18 - 40 years

Official Title Mother-Child Shared Reading

Purpose

The purpose of this study is to examine whether children's characteristics are related to the ways that parents read to children and the questions they ask during storytelling. Mothers will read and record a short story with their child (and submit) and complete an online survey. All research activities will occur online and in your own time.

 

Could this study be right for you?

• Mothers (biological or adoptive) and their 4- to 5-year-olds.
• Children must not have a developmental disability,
• Have normal hearing and vision
• Speak English with mothers at home.

Participation is limited to one child per household and to families residing in and completing the study in the United States though participation can occur from anywhere in the United States. We are currently recruiting only Black and White families for this study.

Age Range

4 - 5 years

Official Title Bisexual Health and Relationships Project

Purpose

The purpose of this study is to better understand the health behaviors and health outcomes for married bisexual people. 

Could this study be right for you?

Our study examines the health of married Bi+ (defined as bisexual, pansexual, queer, etc.) people. We are interviewing both Bi+ individuals and their partners over Zoom. We are specifically looking to speak with Bi+ men married to men and Bi+ people of color of any gender.

Age Range

35 - 65 years

Official Title Examining the safety and clinical efficacy of psilocybin therapy for Veterans with PTSD: An open label proof-of-concept trial

Purpose

The study will demonstrate the safety and efficacy of psilocybin in treating post-traumatic stress disorder (PTSD) in veterans. Psilocybin-assisted therapy has shown great promise in treating anxiety symptoms that comprise post-traumatic stress disorder (PTSD).  Current therapeutic treatments for PTSD are difficult to tolerate and limited in efficacy, especially in the US military veteran population. This study will examine the safety and efficacy of two psilocybin sessions, combined with psychotherapy, among military veterans with severe, treatment resistant PTSD.

Could this study be right for you?

Inclusion criteria:

• Be a United States military veteran 

• 21 to 64 years old  

• Have at least a high-school level of education or equivalent (e.g. GED)

• Current diagnosis of PTSD

• Be medically stable as determined by screening for medical problems via a personal interview, a medical questionnaire, a physical examination, an electrocardiogram (ECG), and routine medical blood and urinalysis laboratory tests  

Exclusion criteria:  

• Women who are pregnant

• Cardiovascular conditions: coronary artery disease, stroke, angina, uncontrolled hypertension, a clinically significant ECG abnormality (e.g., atrial fibrilation), artificial heart valve, or TIA in the past year  

• High blood pressure

• History of seizures or epilepsy

Exclusion Criteria varies, please contact Study Coordinator.

 

Age Range

21 - 64 years

Official Title Patterns Of Survivors’ Recovery Trajectories in the ICECAP trial 􀂥POST-ICECAP􀂦

Purpose

The purpose of this study is to describe the physical, neuropsychological outcomes of adults who have experienced an outside of hospital cardiac arrest; and examine any associations between those outcomes and any clinical and/or rehabilitative interventions and/or social determinants of health.

Could this study be right for you?

• Experienced a coma after resuscitation from a cardiac arrest
• Received targeted/controlled body temperature management
• Survived to at least 1 month after experiencing a outside of hospital cardiac arrest

Age Range

18 years and up

Official Title Disrupted eye gaze perception as a biobehavioral marker of social dysfunction: An RDoC investigation

Purpose

This study seeks to understand social functioning across mental health conditions. Social dysfunction is very common in people with mental health conditions; it can negatively impact employment, independent living, and maintaining meaningful relationships. This research is being done to learn if a person's ability to process visual information (including distinguishing other people's eye gaze direction) is a clue to social functioning regardless of diagnosis. This research will identify clinical and brain characteristics in relation to social functioning.

Could this study be right for you?

Patients:

• Diagnosis of a schizophrenia-spectrum disorder or autism spectrum disorder
• Receiving treatment in a mental health or primary care setting
• Experience difficulty in social functioning

Health Volunteers: 

• No history of past or current mental health disorder diagnosis
• Experience no difficulty in social functioning

Age Range

14 - 30 years

Official Title Lipid Composition of the Tear Film in Healthy Participants and Dry Eye Disease Patients

Purpose

The purpose of this study is to explore the lipid concentration of the tear film in healthy participants and those who have dry eye disease. 

Could this study be right for you?

Inclusion criteria:

• At least 18 years of age (30 years of age for dry eye disease cohort).
• Good general health (defined by medication use that has not changed within the last month and the absence of medical conditions or treatments that are deemed confounding to the data as determined by the PI)
• Ability to give informed consent
• Willing to spend time for the study; approximately one hour for study assessments
• Either gender

Exclusion criteria:

• Use of any ocular prescription medication (such as but not limited to, glaucoma medications, anti-inflammatory eye drops and Restasis) used within 14 days of the screening visit or started prior to the measurement visit(s).   
• Currently having punctal plugs inserted in lacrimal puncta

Inclusion and Exclusion Criteria varies, please contact Study Coordinator for more information. 

Age Range

18 years and up

Official Title AROMA-NT: Assessment of the Mechanisms of Action of Inhaled Essential Oils and Wearable TENS unit device on Nausea

Purpose

The purpose of this research study is to understand how a combination of two aromatic inhalers containing a blend of essential oils and a wearable TENS unit affects nausea and stress in those suffering from chronic nausea and anxiety.

Could this study be right for you?

• Able to understand English
• Nausea going on for longer than 6 months

Age Range

18 - 80 years

Official Title Booster Seat Features that Influence Pediatric Posture and Comfort During Extended Time Periods: On-Road Assessment

Purpose

This study will help identify how booster seats influence children’s comfort during car rides and their behaviors. Car seat footrests will also be used to see how children engage with them. Data will be collected during car rides in the caregiver’s personal vehicle. 

Could this study be right for you?

Child is currently riding in a booster seat during travel in the car 

Age Range

5 - 12 years

Official Title Preschooler's Language Use and Media (PLUM) Study

Purpose

This study is designed to investigate media’s role in language development during early childhood. The goal of the proposed work is to examine the relation between the quantity of children’s media use and their language development trajectories, as well as how characteristics of media use (i.e., parent-child joint engagement, interactive media features, and educational content) predict growth in language over time. 

Could this study be right for you?

• Children 3 to 3.5 years of age (36 to 42 months).

 

Age Range

36 - 42 months

Official Title Project Limb Rescue: A pilot study evaluating the feasibility of transcutaneous sensors for the detection of cancer-related lymphedema

Purpose

The goal of this study is to use new, adhesive-based sensors (pads that stick on your skin) to detect lymphedema, and to develop a way for patients to check for lymphedema at home.

This study will assist in distinguishing participants with lymphedema in comparison to participants without lymphedema at rest by using a combination of photoplethysmography (PPG) and bioimpedance (BI). Photoplethysmography is an optical technique that can be used to detect blood volume changes in tissue. Bioimpedance evaluates how tissue responds to an externally applied electrical current.

Could this study be right for you?

• History of cancer related lymphedema, cancer in your arm, or the lymph nodes in the arm
• History of cancer therapy with surgery or radiation involving the axillary basin and upper arm that requires compression or pneumatic therapy
• Physically capable of performing a brief bike riding exercise for about seven minutes
• No metal implants
• Willingness to take off shoes and any metal jewelry
• Not currently pregnant
• Not currently incarcerated

 

Age Range

18 - 90 years

Official Title Project Limb Rescue: A pilot study evaluating the feasibility of transcutaneous sensors for the detection of cancer-related lymphedema.

Purpose

The goal of the study is to test the success of using two types of sensors at rest after a bike exercise on volunteers with and without lymphedema, to look for differences in their readings. This part of the study will be testing persons who do not have lymphedema.

 

Could this study be right for you?

• No history of cancer related to lymphedema, cancer in your arm, or the lymph nodes in the arm
• Able to complete a brief biking exercise for about seven minutes
• No metal implants
• Willingness to take off shoes and any metal jewelry
• Not currently pregnant
• Not currently incarcerated
• Your participation will involve completing an online or over the phone screening.
• This visit will take approximately 2.5 hours.

Age Range

18 - 90 years